Heart Attack

Ages 45 Years & Older

Do you have poor circulation?

Have you considered participating in a clinical study?

Participating in a clinical study can improve future treatment options for you and other people with cardiovascular diseases.

Research has shown that treatment with semaglutide may reduce the risk of stroke and heart attack in people with type 2 diabetes.

In a study called SELECT, we will check to see if semaglutide reduces the risk of cardiovascular events such as heart attack and stroke in people with overweight or obesity. 

You may qualify to participate in the SELECT study if: 

  • You have had a brain attack (stroke), or heart attack (myocardial infarction), or have poor circulation (peripheral arterial disease)
  • You are 45 years old or older
  • You are living with overweight or obesity
  • You are able to attend regular clinic visits and receive phone calls over a period of 3-5 years.

If you qualified to participate the following would be provided at no cost to you: study-related care, including regular health check-ups, general talks with a dedicated team of doctors and nurses, guidance on healthy lifestyle choices.

Majority of people at high risk of stroke are not routinely screened for common risk factors such as Atrial Fibrillation

Today, stroke remains the second leading cause of death, although many cases are preventable.

The Economist Intelligence Unit (EIU) “Preventing Stroke: Uneven Progress,” report – sponsored by The Bristol Myers Squibb-Pfizer Alliance – includes an analysis of the progress made by 20 countries in implementing stroke prevention policies. One finding was that efforts to screen people for stroke risk factors, including Atrial Fibrillation and hypertension, remain low, even in countries with established health care and developed economies. For example, on average, more than 75 percent of people aged 65 and older are not being screened for Atrial Fibrillation during routine primary care examinations, even though this population is at high risk for stroke. Additionally, the report highlighted a disconnect between established best practices and everyday clinical practice, including gaps in the training of health care professionals to properly identify and treat stroke risks.

Stroke is an enormous burden and costs more than US $80 billion each year in the United States and Europe, including both health care costs and other expenses such as lost productivity. Data amassed from population studies in different countries tell us that as many as about one of every four people who suffers an ischemic stroke – the most common kind – had underlying Atrial Fibrillation that went undiagnosed. Additionally, in more than one-quarter of patients with no history of cardiovascular disease, stroke is the first clinical manifestation of Atrial Fibrillation. Modest improvements in diagnosis and treatment of stroke risk factors could save billions of dollars and help prevent many deaths.

The Bristol Myers Squibb-Pfizer Alliance has committed to investing in initiatives that drive insights, education, awareness and action to improve screening of stroke risk factors and reduce the incidence of stroke. It is working to drive better understanding of the barriers to earlier detection and identify potential strategies to address these through a multifaceted approach that includes support of investigator-initiated studies, investment in innovative commercial pilots, and support of advocacy and payer initiatives throughout the world.

One of these barriers is the absence of clear screening protocols and guidance on when and how to assess a patient for Atrial Fibrillation, which remains an obstacle to early diagnosis and treatment. Existing data shows that opportunistic screening (screening conducted when a patient consults a healthcare professional for another purpose) for Atrial Fibrillation not showing any symptoms is cost-effective. Medical guidelines, including from the European Society of Cardiology, are beginning to recommend screening for Atrial Fibrillation in patients over the age of 65.

However, to implement broader screening approaches (systematic screening) at the clinic level, the results of large, randomized controlled screening studies will be important to demonstrate cost-effectiveness, identify which populations may benefit the most, and inform guidelines and policy development. There is emerging evidence in support of systematic screening, including through the 27,000-patient StrokeSTOP trial in Sweden expected to report out data in 2019.

Among other things, the “Preventing Stroke: Uneven Progress,” report concluded that future policies to prevent stroke should focus on integrated strategies to improve education around risk factors and implement opportunistic and/or systematic screenings to detect risk factors. By improving screening and early diagnosis, The Bristol Myers Squibb-Pfizer Alliance – in collaboration with other key partners – can potentially help prevent strokes and related deaths.

Contact Us to Participate

If you qualify to participate in a clinical trial based upon one of your medical conditions, then the medical care and medication for that medical condition will be provided at no cost to you and you will receive financial compensation for your time & travel.

Tell us a little bit about yourself and we’ll contact you for further information to determine eligibility for current and future studies.

Please note that any information you provide below is stored securely and will not be shared with anyone outside of Oviedo Medical Research. We will use this information only to help us determine if you qualify for participation in one of our studies.

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